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COVID-19 Treatment Resources

CenCal Health is dedicated to keeping our providers up to date with the most current information for the treatment of COVID-19.   The provided information gives details on the use of the pharmacy benefit and medical benefit for COVID-19 treatment.

There is no cost to members for medically needed screening, testing, and treatment for Coronavirus.

COVID-19 National Institutes of Health Guidelines

The following National Institutes of Health (NIH) COVID-19 Treatment Guidelines provide clinicians with evidence-based recommendations on the management of COVID-19 and are revised with the emerging, rapidly evolving COVID-19 treatment options: NIH COVID-19 Treatment Guidelines

For more information on COVID-19 treatments, including product fact sheets and California Treatment Centers, visit

COVID-19 Treatment Options


Pharmacy  Benefit 

(Billed by a pharmacy)

Medical  Benefit

(Billed on a medical claim)

Medication/Vaccine or Test

Medi-Cal Rx

Medi-Cal FFS

CenCal Health Benefit

Paxlovid (nirmatrelvir/ritonavir)




Lagevrio (molnupiravir)




Veklury (remdesivir)




*CenCal Health Medical Benefit Coverage: Infused therapeutics with appropriate procedure codes can be billed to CenCal Health on a medical claim once FDA-approved (i.e., remdesivir).  As infused therapeutic options become FDA-approved and supported by DHCS, NIH Treatment Guidelines, CenCal Health is responsible for coverage if billed on a medical claim

Medi-Cal Rx, New Resources for Providers: COVID-19 Testing and Treatment Support

Medi-Cal Rx is pleased to partner with the California Department of Public Health (CDPH) to announce the publication of new resources  to support providers in assessing the need for and the delivery of COVID-19 treatment to Medi-Cal beneficiaries.

Additional Medi-Cal Rx resources can be found in the Medi-Cal Rx Provider Manual, Section 17.0: COVID-19 Vaccines, OTC Antigen Test Kits, and Therapeutics: Coverage and Reimbursements.

For additional helpful information for Providers regarding COVID-19 local screening & testing, visit